Hi @lzpons and welcome to the Joulescope forum! We are still working to improve the Joulescope UI macOS support. We have many reports that the distributed Joulescope UI dmg does not work on macOS 12. Are you running Homebrew? I have several people that seem to have success with this:
brew install python@3.8
pip3.8 install -U joulescope_ui
Then, to run the Joulescope UI:
python3.8 -m joulescope_ui UI
(from Can't launch Joulescope UI on macOS - #6 by mliberty)
Note that even if this works, you will likely run into issue #171. We continue to work on Joulescope UI 1.x which should address many of these issues!